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Arch Gynecol Obstet. 1995;256(3):115-23.

The effect of preconceptional multivitamin supplementation on the menstrual cycle.

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  • 1Department of Human Genetics and Teratology, National Institute of Hygiene, WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary.


The database of the Hungarian randomised controlled trial of periconceptional multivitamin supplementation for the prevention of neural-tube defects was used to evaluate the length of the pre- and postovulatory phases of the menstrual cycle before and during multivitamin supplementation. The female cycle was more regular (i.e., the variance was lower) during the multivitamin supplementation.

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