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Allergy. 1995 Apr;50(4):359-61.

Hypersensitivity to cefuroxime with good tolerance to other betalactams.

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Servicio Alergología, Hospital Xeral-Cíes, Vigo, Pontevedral, Spain.


A 60-year-old man developed an anaphylactic reaction immediately after administration of intramuscular sodium cefuroxime. By means of oral controlled challenge, the reaction was reproduced with a smaller dose of cefuroxime axetil. Cross-reactivity with other betalactam antibiotics was ruled out by in vivo tests. This case supports once again the relevance of the side-chain in betalactam allergy.

[Indexed for MEDLINE]

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