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Am J Obstet Gynecol. 1995 Sep;173(3 Pt 1):890-3.

Ultrasonographic bone characteristics during normal pregnancy: longitudinal and cross-sectional evaluation.

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1
Department of Obstetrics and Gynecology Piero Fioretti, University of Pisa, Italy.

Abstract

OBJECTIVE:

We evaluated the pattern of bone density during pregnancy by radiation-free ultrasonographic densitometry.

STUDY DESIGN:

In a longitudinal study we measured bone mineral density in a group of 10 normal primiparous women, from the fourteenth to the thirty-eighth weeks of pregnancy. In a cross-sectional study bone mineral density was determined in a group of 85 normal primiparous women, in different weeks of pregnancy.

RESULTS:

In the longitudinal study ultrasonographic bone density was stable in the first part of pregnancy, whereas a significant (p < 0.05) decrease was evidenced during the third trimester. A negative correlation between bone density and weeks of pregnancy (p < 0.0001) was evidenced in the cross-sectional study.

CONCLUSION:

During physiologic pregnancy the calcium mobilization from the maternal bone stores to accomplish the fetal needs can cause a significant decrease in maternal bone density in the last trimester of gestation.

PMID:
7573264
[Indexed for MEDLINE]
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