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Nephron. 1995;70(2):193-6.

Oral activated charcoal in patients with uremic pruritus.

Author information

1
Institute of Clinical Medicine I, University of Pisa, Italy.

Abstract

Twenty-three chronic uremic patients on maintenance hemodialysis and suffering from severe pruritus were treated with activated powdered charcoal (6 g daily p.o.). In 10 patients pruritus disappeared completely, and in 10 other patients a partial effect was observed. The favorable results persisted for several weeks after discontinuation of the treatment. Only 3 cases were totally unresponsive. No relevant undesirable side effects were observed with the exception of 1 case who showed treatment intolerance. It is concluded that activated charcoal per os is a safe, effective, and low-cost therapy for patients with uremic pruritus, but its mechanism of action is unknown.

PMID:
7566302
DOI:
10.1159/000188582
[Indexed for MEDLINE]

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