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Heredity (Edinb). 1995 Aug;75 ( Pt 2):113-25.

Recombination in single and double heterozygotes for two partially overlapping inversions in chromosome 1 of the house mouse.

Author information

1
Institute of Cytology and Genetics, Novosibirsk, Russia.

Abstract

Recombination frequency, chiasmata and chromatid interference were studied by means of analysis of meiotic configurations in diakinesis and metaphase II in single and double heterozygotes for the partially overlapping inversions In(1)1Rk and In(1)12Rk in chromosome 1 of the house mouse. Recombination frequency in the inverted regions was decreased in single heterozygotes and increased in the double heterozygotes as compared to normal homozygotes. Chiasmata in the inverted regions in the double heterozygotes did not interfere with each other. A significant excess of 4-chromatid double exchanges in the inverted regions was detected in the double heterozygotes.

PMID:
7558886
[Indexed for MEDLINE]

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