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FEMS Microbiol Lett. 1995 Sep 15;131(3):235-42.

Structure and partitioning of bacterial DNA: determined by a balance of compaction and expansion forces?

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1
Institute for Molecular Cell Biology, BioCentrum, University of Amsterdam, The Netherlands.

Abstract

The mechanisms that determine chromosome structure and chromosome partitioning in bacteria are largely unknown. Here we discuss two hypotheses: (i) the structure of the Escherichia coli nucleoid is determined by DNA binding proteins and DNA supercoiling, representing a compaction force on the one hand, and by the coupled transcription/translation/translocation of plasma membrane and cell wall proteins, representing an expansion force on the other hand; (ii) the two forces are important for the partitioning process of chromosomes.

[Indexed for MEDLINE]

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