Send to

Choose Destination
Eur J Biochem. 1995 Aug 15;232(1):188-91.

Reversible binding and inhibition of catalase by nitric oxide.

Author information

Department of Biochemistry, University of Cambridge, England.


The interactions between nitric oxide (NO), H2O2, and catalase were investigated. H2O2 did not cause detectable breakdown of NO in the absence of catalase, but did cause NO breakdown in the presence of catalase. Catalase bound NO, and NO rapidly and reversibly inhibited catalase with a Ki of 0.18 microM. The significance of these results for NO cytotoxicity is discussed.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center