Format

Send to

Choose Destination
Curr Biol. 1995 Jun 1;5(6):615-7.

Integrin-ligand binding. Do integrins use a 'MIDAS touch' to grasp an Asp?

Author information

1
Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

Abstract

Integrins use divalent cations, held within a novel 'MIDAS' motif, for ligand binding. It is proposed that a missing coordination site for the cation is provided by a critical acidic residue in the ligand.

PMID:
7552170
DOI:
10.1016/s0960-9822(95)00124-2
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center