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Curr Opin Nephrol Hypertens. 1995 Jul;4(4):369-73.

Renal toxicity of albumin and other lipoproteins.

Author information

1
CV Therapeutics Inc., Palo Alto, California, USA.

Abstract

Proteinuria may be an independent risk factor for nephrosclerosis. One potential mechanism has emerged with the finding that lipoproteins, including albumin, modulate the biology of mesangial cells and proximal tubular epithelial cells when internalized. Consequent alterations in renal-cell lipid metabolism may underlie some of these effects.

PMID:
7552106
[Indexed for MEDLINE]

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