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Trends Microbiol. 1995 Jul;3(7):275-9.

Growth-phase regulation of plasmid virulence genes in Salmonella.

Author information

1
Dept of Medicine 0640, UCSD School of Medicine, La Jolla, CA 92093-0640, USA.

Abstract

Virulence genes in the genus Salmonella are regulated by growth phase and by environmental signals, which allows a sequential program of expression during infection. Conditions that promote the expression of loci required in systemic infection, including the plasmid-encoded spv genes, are the opposite of the factors that induce genes involved in the invasion of epithelial cells in the gastrointestinal tract.

PMID:
7551642
DOI:
10.1016/s0966-842x(00)88944-1
[Indexed for MEDLINE]

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