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Curr Opin Immunol. 1995 Jun;7(3):375-81.

Molecular mechanisms underlying functional T-cell unresponsiveness.

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1
University of Minnesota Medical School, Department of Medicine, Minneapolis 55455, USA.

Abstract

Evidence from tissue culture experiments and in vivo studies indicates that certain forms of antigen presentation render T cells unresponsive to subsequent antigenic stimulation. Great progress has been made recently in understanding the induction, maintenance, and in vivo relevance of this unresponsive state, called clonal anergy.

PMID:
7546403
DOI:
10.1016/0952-7915(95)80113-8
[Indexed for MEDLINE]

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