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Eur Heart J. 1995 Mar;16(3):424-5.

Tropheryma whippelii endocarditis confirmed by polymerase chain reaction.

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Department of Pathology, General Hospital of Ludwigshafen/Rhein, Germany.


This report concerns a patient with cardiac manifestation of Whipple's disease. For the first time, the gene that encodes the 16s rRNA of Tropheryma whippelii was identified in a native aortic valve by means of a polymerase chain reaction technique. DNA amplification gives evidence of Tropheryma whippelii as a causative organism in infective endocarditis.

[Indexed for MEDLINE]

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