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Curr Opin Cell Biol. 1995 Feb;7(1):118-25.

Intermediate filaments in disease.

Author information

1
Department of Anatomy and Physiology, University of Dundee, UK.

Abstract

Intermediate filaments are major structural proteins encoded by a large multigene family. Their tissue-specific expression makes them important in studies of development, differentiation and pathology. Most intermediate filaments are keratins; recent discoveries of keratin mutations in a range of genetic skin disorders have clarified their role as providing essential structural support for cells in different physical settings.

PMID:
7538772
DOI:
10.1016/0955-0674(95)80053-0
[Indexed for MEDLINE]

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