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Trends Neurosci. 1995 Feb;18(2):89-98.

Exocytotic Ca2+ channels in mammalian central neurons.

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Dept of Physiology, Tufts University School of Medicine, Boston, MA 02111, USA.


Intracellular Ca2+ initiates physiological events as diverse as gene transcription, muscle contraction, cell division and exocytosis. Predictably, the metabolic machinery that elicits and responds to changes in intracellular Ca2+ is correspondingly heterogeneous. This review focuses on one element of this complex web that is of particular importance to neurobiologists: identifying which members of the voltage-dependent Ca(2+)-channel superfamily are responsible for the Ca2+ that enters nerve terminals and elicits vesicular release of chemical transmitters.

[Indexed for MEDLINE]

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