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Trends Microbiol. 1994 Sep;2(9):312-8.

CD46, a primate-specific receptor for measles virus.

Author information

1
Biotechnology Research Institute, National Research Council of Canada, Montréal.

Abstract

Measles virus normally infects only primate cells. The receptor for measles virus has recently been shown to be the complement regulator CD46, also known as membrane cofactor protein. Transfection of rodent cells with human CD46 renders them susceptible to the virus, suggesting that transgenic animals may prove useful for testing antiviral agents and vaccines.

PMID:
7529121
DOI:
10.1016/0966-842x(94)90447-2
[Indexed for MEDLINE]

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