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Antiviral Res. 1994 Jul;24(2-3):205-19.

Multiple effects of interferon on the replication of human immunodeficiency virus type 1.

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1
Oncology Center, Johns Hopkins University, Baltimore, MD 21231.

Abstract

In this review, I shall summarize the major findings about the effect of IFN on the replication of HIV-1 virus in model systems in vitro and will describe the known molecular mechanisms involved in the IFN-mediated inhibition of HIV-1 replication. Finally, I shall relate these findings to the unique features of the HIV-1 replication cycle.

PMID:
7526792
DOI:
10.1016/0166-3542(94)90068-x
[Indexed for MEDLINE]

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