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Immunol Today. 1994 Sep;15(9):437-42.

The CD19/CD21 signal transduction complex of B lymphocytes.

Author information

1
Dept of Immunology, Duke University Medical Center, Durham, NC 27710.

Abstract

CD19 and CD21 are B-cell surface molecules that associate with each other and with CD81 and Leu-13 to generate a signal transduction complex that is independent of the antigen receptor. Current studies, reviewed here by Thomas Tedder, Liang-Ji Zhou and Pablo Engel, indicate an important biological role for this protein complex in the regulation of B-cell development and activation.

PMID:
7524521
DOI:
10.1016/0167-5699(94)90274-7
[Indexed for MEDLINE]

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