Format

Send to

Choose Destination
Bioessays. 1994 Jun;16(6):425-30.

RNA polymerase: structural determinant of the chromatin loop and the chromosome.

Author information

1
CRC Nuclear Structure and Function Research Group, Sir William Dunn School of Pathology, University of Oxford, UK.

Abstract

Current models for RNA synthesis involve an RNA polymerase that tracks along a static template. However, research on chromatin loops suggests that the template slides past a stationary polymerase; individual polymerases tie the chromatin fibre into loops and clusters of polymerases determine the basic structure of the interphase and metaphase chromosome. RNA polymerase is then both a player and a manager of the chromosome loop.

PMID:
7521639
DOI:
10.1002/bies.950160611
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center