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FEBS Lett. 1994 Aug 29;351(1):41-4.

Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells.

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1
Department of Medicine University College London Medical School, Rayne Institute, UK.

Abstract

Src-related cytoplasmic PTKs are physically and functionally associated with cell surface receptors and are involved in signal transduction. In this paper we report the identification of src-related proteins p59fyn, pp60c-src and p62yes in human microvascular endothelial cells cultured from normal human skin and their physical association with the thrombospondin receptor CD36. Such an association represents a potential signalling pathway by which thrombospondin may regulate angiogenesis.

PMID:
7521304
DOI:
10.1016/0014-5793(94)00814-0
[Indexed for MEDLINE]
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