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Intern Med. 1993 Nov;32(11):869-71.

Leukemoid reaction associated with diabetic ketoacidosis--with measurement of plasma levels of granulocyte colony-stimulating factor.

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First Department of Internal Medicine, Oita Prefectural Hospital.


A 40-year-old man with diabetic ketoacidosis showed marked leukocytosis reaching 60,970/mm3 which subsided within 5 days to a level of 4,140/mm3. He had no evidence of infection. During the entire clinical course, no elevation of granulocyte colony-stimulating factor (G-CSF) was observed. No case of leukemoid reaction associated with diabetic ketoacidosis has been reported with the determination of plasma G-CSF levels.

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