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Urology. 1994 Mar;43(3):408-10.

Prostate-specific antigen decline after casodex withdrawal: evidence for an antiandrogen withdrawal syndrome.

Author information

1
Department of Medicine, University of California, San Francisco.

Abstract

OBJECTIVE:

To evaluate the relationship between antiandrogen withdrawal and change in prostate-specific antigen (PSA) when the antiandrogen in question is other than flutamide.

METHODS:

Presented is a case of a patient in whom the antiandrogen casodex was discontinued after clinical progression despite combined androgen blockade.

RESULTS:

A transient decline in serum PSA was observed after casodex withdrawal.

CONCLUSIONS:

The relationship between antiandrogen withdrawal and a change in PSA may be a general phenomenon, not unique to flutamide.

PMID:
7510915
DOI:
10.1016/0090-4295(94)90092-2
[Indexed for MEDLINE]

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