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Curr Opin Cell Biol. 1993 Aug;5(4):647-52.

Plasmalemmal caveolae and GPI-anchored membrane proteins.

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Department of Cell Biology and Neuroscience, University of Texas, Southwestern Medical Center, Dallas 75235.


Caveolae are essential endocytic organelles that use glycosyl-phosphatidyl-inositol (GPI)-anchored membrane proteins to concentrate low molecular weight substances before delivery to the cell. Caveolae and GPI-anchored proteins are uniquely adapted for this task. Recent advances suggest that this endocytic pathway also has an important role in modulating the interaction of a cell with its environment. Many vital functions that occur in this organelle remain to be discovered.

[Indexed for MEDLINE]

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