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Arch Pathol Lab Med. 1995 Dec;119(12):1170-3.

Postirradiation colitis cystica profunda. Case report and literature review.

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Department of Pathology, Queen Mary Hospital, University of Hong Kong.


We report a rare case of rectosigmoid stricture associated with colitis cystica profunda that occurred 21 years after local therapeutic irradiation given for carcinoma of the bladder. We reviewed the literature and compared the clinical features, etiology, and macroscopic findings. The pathogenesis of the lesion may be related to repeated ulceration and regeneration, while chronic colonic ischemia may also play a role. The recognition of this rare entity is important because of its low-power "penetrating" architecture, which may be mistaken histologically as well-differentiated adenocarcinoma.

[Indexed for MEDLINE]

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