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Am J Obstet Gynecol. 1995 Nov;173(5):1513-7.

Fetal fibronectin as a selection criterion for induction of term labor.

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1
Department of Obstetrics and Gynecology, University of Vienna, Austria.

Abstract

OBJECTIVE:

We examined whether the presence of fetal fibronectin in cervicovaginal secretions can be used as a selection criterion for induction of labor at term.

STUDY DESIGN:

Cervicovaginal secretions of 64 women who were scheduled for induction of labor were examined for fetal fibronectin and divided into group A (positive for fibronectin) and group B (negative for fibronectin). Both groups were examined for Bishop score, the number of prostaglandin tablets administered, and the interval between induction of labor and delivery.

RESULTS:

In group A the interval between induction of labor and delivery was significantly shorter (p < 0.0001) than in group B. The number of prostaglandin tablets administered to group A was likewise significantly lower (p < 0.0001). Unsuccessful induction of labor only occurred in women with fibronectin-negative cervicovaginal secretions.

CONCLUSION:

The assessment of the fibronectin content of cervicovaginal secretions constitutes a viable instrument in the decision-making process preceding induction of labor.

PMID:
7503193
[Indexed for MEDLINE]
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