Genomic structure and alternative splicing of the murine bhk/ctk/ntk gene

FEBS Lett. 1995 Nov 13;375(1-2):50-2. doi: 10.1016/0014-5793(95)01154-7.

Abstract

Recently, we and others have cloned cDNAs encoding a second member of the Csk family of inhibitory protein kinases, which we termed Bhk [M.A. Ershler et al. (1994) Dokl. Akad. Nauk. 339, 679-683]. In the present study, two new distinct types of bhk mRNA were found in addition to the third form described previously. Analysis of the bhk genomic structure established that three exons participate in the alternative splicing of bhk mRNA.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing*
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Brain / enzymology*
  • Cloning, Molecular
  • DNA Primers
  • DNA, Complementary
  • Genomic Library
  • Humans
  • Mice
  • Mice, Inbred Strains
  • Molecular Sequence Data
  • Polymerase Chain Reaction
  • Protein-Tyrosine Kinases / biosynthesis
  • Protein-Tyrosine Kinases / genetics*
  • Proto-Oncogene Proteins pp60(c-src)*
  • RNA, Messenger / metabolism
  • Sequence Homology, Amino Acid
  • Sequence Homology, Nucleic Acid

Substances

  • DNA Primers
  • DNA, Complementary
  • RNA, Messenger
  • Matk protein, mouse
  • Protein-Tyrosine Kinases
  • Proto-Oncogene Proteins pp60(c-src)

Associated data

  • GENBANK/X89723
  • GENBANK/X89724