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J Steroid Biochem Mol Biol. 1995 Nov;55(2):229-31.

Pharmacokinetics of tamoxifen in premenopausal and postmenopausal women with breast cancer.

Author information

1
Department of Clinical Biology, Haukeland University Hospital, Bergen, Norway.

Abstract

We measured the serum levels of tamoxifen and 5 of its metabolites in serum from 7 premenopausal and 9 postmenopausal women during the first 56 days of treatment. The serum levels of N-desdimethyltamoxifen were higher in postmenopausal women compared to premenopausal women (P < 0.02). A similar trend was observed for N-desmethyltamoxifen (P = 0.06).

PMID:
7495702
DOI:
10.1016/0960-0760(95)00169-z
[Indexed for MEDLINE]

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