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Curr Opin Cell Biol. 1995 Aug;7(4):587-94.

Molecular motors, membrane movements and physiology: emerging roles for myosins.

Author information

1
Department of Biology, Yale University, New Haven, CT 06520, USA.

Abstract

Myosins are a large family of structurally diverse mechanoenzymes which, upon interaction with actin filaments, convert energy from ATP hydrolysis into mechanical force. Consistent with the ubiquitous association of actin with membranes, many of these novel myosins are membrane-associated. In the past two years, evidence has emerged that suggests roles for actin-based molecular motors in a wide range of membrane phenomena such as cell locomotion, phagocytosis, secretion, organelle transport, signal transduction and mechanoregulation of membrane protein function.

PMID:
7495580
DOI:
10.1016/0955-0674(95)80017-4
[Indexed for MEDLINE]

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