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Immunol Today. 1995 Nov;16(11):534-9.

Involvement of B-1 cells in mucosal immunity and autoimmunity.

Author information

1
Dept of Medical Chemistry, Faculty of Medicine, Kyoto University, Japan.

Abstract

B-1 cells are distinguished from conventional B cells by their anatomical localization, surface phenotypes and functional characteristics. The physiological functions and pathological roles of these cells remain controversial. In this review, Masao Murakami and Tasuku Honjo summarize recent evidence for the involvement of B-1 cells in mucosal immunity and autoimmunity, and discuss the relationship between these phenomena.

PMID:
7495491
DOI:
10.1016/0167-5699(95)80047-6
[Indexed for MEDLINE]

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