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J Virol. 1995 Dec;69(12):8151-4.

Configuration of latent varicella-zoster virus DNA.

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1
Department of Neurology, University of Colorado Health Sciences Center, Denver 80262, USA.

Abstract

The configuration of latent varicella-zoster virus (VZV) DNA was analyzed by PCR. Template DNA for both internal and terminal VZV primers was present in a 1:1 ratio in ganglionic DNA, compared with a 15:1 ratio in DNA extracted from VZV virions, indicating that the VZV genomic termini are adjacent in latently infected human ganglia.

PMID:
7494340
PMCID:
PMC189772
[Indexed for MEDLINE]
Free PMC Article
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