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Antimicrob Agents Chemother. 1995 Jul;39(7):1596-8.

Susceptibility of Acanthamoeba castellanii to contact lens disinfecting solutions.

Author information

1
Institute of Microbiology and Virology, University of Sassari, Italy.

Abstract

A corneal isolate of Acanthamoeba castellanii was exposed to commercial contact lens disinfecting solutions containing hydrogen peroxide, benzalkonium chloride, polyaminopropyl biguanide, polyquaternium 1, and chlorhexidine-thimerosal. The minimum trophozoite amebicidal concentration and exposure times required to kill trophozoites and cysts were determined. Solutions containing hydrogen peroxide or chlorhexidine-thimerosal were active against both trophozoites and cysts. The benzalkonium chloride-based solution was effective only against trophozoites. Solutions containing polyaminopropyl biguanide or polyquaternium 1 were completely ineffective. The need for adequate exposure times must be stressed.

PMID:
7492111
PMCID:
PMC162788
DOI:
10.1128/aac.39.7.1596
[Indexed for MEDLINE]
Free PMC Article

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