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Am J Ophthalmol. 1995 Nov;120(5):671-3.

Interleukin-10 in the vitreous of patients with primary intraocular lymphoma.

Author information

1
Laboratory of Immunology, National Eye Institute, Bethesda, MD 20892-1858, USA.

Abstract

PURPOSE:

To find an accurate and simple method to diagnose primary intraocular lymphoma.

METHODS:

We prospectively analyzed concentrations of interleukin-10, interleukin-1, interleukin-2, interleukin-4, and interleukin-6 in vitrectomy specimens from three patients with primary intraocular lymphoma and five patients with uveitis by enzyme-linked immunosorbent assay.

RESULTS:

Interleukin-10 in the vitreous was detected in patients with primary intraocular lymphoma. Interleukin-10 levels correlated with clinical activity and the number of malignant cells.

CONCLUSION:

Concentrations of interleukin-10 in the vitreous may be a helpful clue to both clinicians and pathologists in diagnosing primary intraocular lymphoma.

PMID:
7485372
DOI:
10.1016/s0002-9394(14)72217-2
[Indexed for MEDLINE]

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