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Plasmid. 1995 Jul;34(1):62-7.

Multidrug resistance plasmid pSK108 from coagulase-negative staphylococci; relationships to Staphylococcus aureus qacC plasmids.

Author information

1
School of Biological Sciences, University of Sydney, New South Wales, Australia.

Abstract

The 2.4-kb Staphylococcus epidermidis plasmid, pSK108, encodes a qacC multidrug resistance determinant. Sequence analysis has revealed that pSK108 is a member of the pC194 family of rolling circle replicating plasmids and suggests that the DNA segment containing qacC, which is bounded by the replication nick site and the minus origin palA, represents a resistance gene cassette that has undergone horizontal genetic exchange.

PMID:
7480172
DOI:
10.1006/plas.1995.1034
[Indexed for MEDLINE]

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