Format

Send to

Choose Destination
See comment in PubMed Commons below
Nephrol Dial Transplant. 1995;10(7):1162-5.

Wegener granulomatosis is associated to exposure to silicon compounds: a case-control study.

Author information

1
Department of Nephrology-Hypertension, University of Antwerp, Belgium.

Erratum in

  • Nephrol Dial Transplant 1995 Nov;10(11):2168.

Abstract

Wegener granulomatosis is a rare disease of unknown aetiology. In the majority of these patients the kidney is involved in the disease process. We performed a case-control study to evaluate the role of occupational exposure in the development of Wegener granulomatosis with renal involvement. The occupational histories of 16 cases with clearly established diagnosis of Wegener granulomatosis with renal involvement were compared with those of 32 age- and sex-matched controls. It was observed that inhalation of silicon-containing compounds such as silica and grain dust gave a nearly sevenfold risk for Wegener granulomatosis. Further epidemiological and experimental work needs to be performed in order to corroborate these findings.

Comment in

PMID:
7478118
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center