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J Rheumatol. 1995 Aug;22(8):1461-5.

Technetium-99m labelled polyclonal human IgG scintigraphy before and 26 weeks after initiation of parenteral gold treatment in patients with rheumatoid arthritis.

Author information

1
Department of Rheumatology, University Hospital Leiden, The Netherlands.

Abstract

OBJECTIVE:

To determine effectiveness of technetium-99m labelled polyclonal human immunoglobulin G (99mTc-IgG) scintigraphy to monitor variation in arthritis activity in patients with rheumatoid arthritis (RA).

METHODS:

The results of semiquantitative 99mTc-IgG scintigraphy were compared with those of examination before and 26 weeks after initiation of parenteral gold treatment in 19 patients with RA.

RESULTS:

Clinical and laboratory variables of arthritis activity as well as the scores of 99mTc-IgG scintigraphy were significantly lower after gold treatment compared to the scores before treatment. However, the difference between the mean scores of 99mTc-IgG scintigraphy before and after treatment was statistically significant for more joints than such difference in scores for joint pain and joint swelling.

CONCLUSION:

99mTc-IgG scintigraphy is able to reflect variations in arthritis activity in patients with RA.

PMID:
7473466
[Indexed for MEDLINE]

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