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Fortschr Med. 1980 Apr 24;98(16):606-7.

[The uric acid lowering effect of protein-rich diets. Behavior of human uric acid metabolism under reducing diet forms with varied protein content].

[Article in German]


The effect of a 60 g protein diet was compared to a 120 g protein diet. Under nutrition with 60 g protein/day the uric acid clearance dropped from 6.3 +/- 2.2 ml/min to 4.9 +/- 1.6 ml/min. During application of 120 g protein/day uric acid clearance was not reduced. Therefore serum uric acid concentration dropped from 7.7 +/- 0.5 mg/dl to 6.4 +/- 0.5 mg/dl. The supply of 120 g protein/day has such a strong uricosuric action that the otherwise occurring inhibition of uric acid clearance during weight reduction can be balanced.

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