Facilitation of discriminated rearing-avoidance in rats with hippocampal lesions

Percept Mot Skills. 1980 Feb;50(1):56-8. doi: 10.2466/pms.1980.50.1.56.

Abstract

Effects of bilateral hippocampal lesions were investigated in a newly developed discriminated rearing-avoidance task. A significant facilitation of avoidance conditioning was found in rats with hippocampal lesions. The over-all escape topography of the hippocampal-lesioned rats was mostly jumping whereas that of the controls was rearing. These findings suggest that the hippocampal lesion increases reactivity to shock.

MeSH terms

  • Animals
  • Avoidance Learning / physiology*
  • Behavior, Animal / physiology
  • Discrimination Learning / physiology*
  • Electroshock
  • Functional Laterality
  • Hippocampus / physiology*
  • Male
  • Rats