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J Nutr. 1980 Apr;110(4):662-8.

Histamine and ascorbic acid in human blood.

Abstract

Analysis of 437 human blood samples has shown that when the plasma-reduced ascorbic acid level falls below 1 mg/100 ml, the whole blood histamine level increases exponentially as the ascorbic acid level decreases. When the ascorbic acid level falls below 0.7 mg/100 ml, there is a highly significant increase in the blood histamine level. Oral administration of ascorbic acid (1 g daily for 3 days) to 11 selected volunteers resulted in a reduction of the blood histamine level in every instance.

PMID:
7365537
DOI:
10.1093/jn/110.4.662
[Indexed for MEDLINE]

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