Format

Send to

Choose Destination
See comment in PubMed Commons below
Hear Res. 1980 Mar;2(2):111-3.

Ototoxicity of kanamycin in developing rats: relationship with the onset of the auditory function.

Abstract

In order to test the relationship between the ototoxicity of kanamycin and the onset of the auditory function, two groups of developing rats were intoxicated with kanamycin before and after the period of onset of cochlear potentials (8th postnatal day). Kanamycin was shown to have a weak ototoxic effect before the 8th postnatal day and a strong ototoxic effect after this period. These results indicate a critical period of sensitivity to ototoxic antibiotics during auditory development.

PMID:
7364666
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center