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Nature. 1980 Feb 7;283(5747):545-9.

Structure of the junction between communicating cells.


An 18-A resolution map of the 'gap junction' has been obtained by electron microscopy. The protein oligomer in the junctional membranes, the 'connexon', is a cyclinder composed of six subunits which are titled around its axis. Analysis of two different subunit configurations suggests how the connexon might regulate the passage of small molecules between cell interiors.

[Indexed for MEDLINE]

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