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J Nat Prod. 1981 Nov-Dec;44(6):648-55.

Hypoglycemic activity of polypeptide-p from a plant source.

Abstract

A hypoglycemic peptide, Polypeptide-p, has been isolated from fruit, seeds, and tissue of Momordica charantia Linn (bitter gourd). Amino acid analysis indicates a minimum molecular weight of approximately 11,000 (166 residues). Polypeptide-p is a very effective hypoglycemic agent when administered subcutaneously to gerbils, langurs, and humans.

PMID:
7334382
[Indexed for MEDLINE]
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