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Am J Hum Genet. 1981 Nov;33(6):894-9.

Evidence for heterosis in the HLA system.

Abstract

The number of persons with homozygous HLA haplotypes in several groups of South American Indians was 39% less than that expected assuming unmodified equilibrium. In a subpopulation of 122 persons whose parents' HLA constitutions were known, there were 56% fewer homozygous persons than expected. This deficit was widely distributed in different haplotypes and different tribal groups.

PMID:
7325154
PMCID:
PMC1685167
[Indexed for MEDLINE]
Free PMC Article

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