Brother and sister with trisomy 10p. 46,XY,(22p+)mat; 46,XX,(22p+)mat

Hum Genet. 1978 Nov 24;45(1):71-5. doi: 10.1007/BF00277575.

Abstract

Since the usefulness of chromosome differential banding techniques has become fully established, several descriptions of chromosome 10 short arm trisomy have been published (Schleiermacher et al., 1974; Roux et al., 1974; Cantu et al., 1975; Grosse et al., 1975; Moric-Petrovic et al., 1976; Turleau et al., 1976; Johnson et al., 1977; Yunis and Lewandowski, 1977). The present report deals with a mother who is a carrier of a reciprocal translocation between chromosome 22 and 10, which has resulted in two children with a 10p trisomy.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / genetics
  • Child
  • Child, Preschool
  • Chromosomes, Human, 21-22 and Y
  • Chromosomes, Human, 6-12 and X*
  • Female
  • Humans
  • Intellectual Disability / genetics
  • Male
  • Translocation, Genetic
  • Trisomy*