Send to

Choose Destination
Control Clin Trials. 1981 Jun;2(2):93-113.

Introduction to sample size determination and power analysis for clinical trials.


The importance of sample size evaluation in clinical trials is reviewed and a general method is presented from which specific equations are derived for sample size determination or the analysis of power for a wide variety os statistical procedures. The method is discussed and illustrated in relation to the t test, tests for proportions, tests of survival time, and tests for correlations as they commonly occur in clinical trials. Most of the specific equations reduce to a simple general form for which tables are presented.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center