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Am J Psychiatry. 1981 Aug;138(8):1098-101.

CSF GABA in normal subjects and patients with depression, schizophrenia, mania, and anorexia nervosa.

Abstract

The authors examined the CSF GABA of 87 subjects: 29 normal control subjects, 11 patients with schizophrenia, 26 with depression, 6 with mania, and 15 with anorexia nervosa. Depressed patients had significantly lower CSF GABA levels than did normal subjects. This finding suggests that GABA may have a direct or indirect association with depressive affective disorders.

PMID:
7258390
DOI:
10.1176/ajp.138.8.1098
[Indexed for MEDLINE]

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