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Cancer. 1980 May 1;45(9):2330-6.

Tobacco-induced changes in oral leukoplakic epithelium.


A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron-like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice-like appearance. The clinical and histologic changes were only observed in tobacco users, and appeared to be associated particularly with use of pipes, snuff, and hooklis.

[Indexed for MEDLINE]

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