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Nature. 1977 Sep 8;269(5624):122-6.

In vitro synthesis of infectious DNA of murine leukaemia virus.

Abstract

DNA synthesised in vitro by purified virions of murine leukaemia virus is infectious. Neither RNA nor protein is required for infectivity. Transfection with reverse trancriptase product shows a single-hit dose response and results in the production of complete, infectious virus.

PMID:
71657
DOI:
10.1038/269122a0
[Indexed for MEDLINE]

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