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Nucleic Acids Res. 1982 Sep 11;10(17):5303-18.

Recognition of protein coding regions in DNA sequences.

Abstract

We give a test for protein coding regions which is based on simple and universal differences between protein-coding and noncoding DNA. The test is simple enough to use without a computer and is completely objective. The test has been thoroughly proven on 400,000 bases of sequence data: it misclassifies 5% of the regions tested and gives an answer of "No Opinion" one fifth of the time. We predict some new coding and noncoding regions in published sequences.

PMID:
7145702
PMCID:
PMC320873
DOI:
10.1093/nar/10.17.5303
[Indexed for MEDLINE]
Free PMC Article

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