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Neurosci Lett. 1982 Aug 31;31(3):323-8.

High level of tubulin microheterogeneity in the mouse brain.

Abstract

Using a high resolution isoelectric focusing method, we have demonstrated a high level of tubulin heterogeneity in mouse brain: 21 isotubulins were identified. Determination of the apparent molecular weight and analysis of the peptide map of each isotubulin species allowed us to identify 7 alpha and 14 beta tubulin subunits. Furthermore, variations in this tubulin population during brain development were confirmed; in particular, an increase in the number of beta isotubulins was observed at the beginning of the postnatal period.

PMID:
7133567
DOI:
10.1016/0304-3940(82)90041-6
[Indexed for MEDLINE]

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