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Brain Res. 1982 May 6;239(1):289-93.

Thalamic bursting mechanism: an inward slow current revealed by membrane hyperpolarization.

Abstract

Hyperpolarization of the ventrolateral thalamic cell membrane reveals a slow inward current which is not normally observed at the resting membrane potential. The response evoked by depolarizing synaptic potentials or depolarizing current pulses from a hyperpolarized potential consists of a burst of action potentials superimposed upon a slow voltage response, in contrast to the single active response evoked without the background polarization. We propose that such behavior is caused by a slow inward current that is activated at subthreshold potentials and inactivated or masked at resting potential.

PMID:
7093684
DOI:
10.1016/0006-8993(82)90854-x
[Indexed for MEDLINE]

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