Send to

Choose Destination
See comment in PubMed Commons below
Brain Res. 1982 May 6;239(1):271-4.

Spinal afferents for peripheral osmoreceptors in the rat.


Superfusion of the hepatic portal vein with hypertonic saline solutions increases the electrical activity of the hypothalamo-neurohypophysial tract. Bilateral cervical vagotomy had no effect on this response in all rats studied. Section of the hepatic branch of the vagus abolished the hypothalamic response in only two animals, but injection of xylocaine into the spinal cord at thoracic levels abolished the response in all remaining animals. The results suggest that peripheral osmoreceptors of the portal vein activate the hypothalamo-neurohypophysial system through a spinal afferent pathway.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center